We’ve got to admit, Seth Rogen and Chris Pine are two of our favorite men in Hollywood right now, and they’re both pretty sought after commodities. So when TheWrap learned that they might soon be starring in a film together, our attention was piqued.

Of course, the potential casting reminded us immediately of the unlikely match of Seth and James Franco in “Pineapple Express,” which turned out to be perfect because of their pitch-perfect chemistry together. While Seth and Chris haven’t worked together previously like Seth and James did in “Freak and Geeks,” we still think the comparison fits.

While neither Seth nor Chris have been confirmed for a role in Fox’s long-in-production romantic comedy “This Means War,” TheWrap seems to believe they are the two most likely candidates to land the parts. Each would hypothetically play best friends whose friendship is torn apart after a woman (Reese Witherspoon) moves into their spare room. Their fighting gets so violent that they end up destroying such important New York City landmarks as the Empire State Building and the Statue of Liberty. McG is set to direct it.

The plot seems a little hokey, but we like the idea of Seth and Chris fighting over Reese in a romantic comedy. And it turns out we weren’t so far off on our “Pineapple Express” comparison. James Franco had originally been offered the role of one of the best friends, but has since turned it down. TheWrap seems to think Seth would move over and take the part James gave up, thus allowing him to star opposite Chris.

Fox has been chasing a number of high-profile actors for the character of FDR (one of the best friends and the role for which Seth and Chris had originally been short-listed), according to Production Weekly. In addition to Seth and Chris, Robert Downey Jr. and Matt Damon are potential candidates. But TheWrap got news that Robert isn’t considering the role and that Matt hasn’t even looked at the script yet, which is what helped lead them to their assumption.

“This Means War” was originally purchased by Fox in 1998, which means the project has been sitting in production hell for more than 12 years. While the film now has Reese and McG attached and the script is getting a rewrite from “Role Models’” Tim Dowling, there are no guarantees when or if the film will hit theaters. Still, the idea of Seth and Chris starring opposite each other is enough to get us excited enough to keep an eye on the project into the future.